Organic Acids
Medchemexpress LLC Siynfekl Tfa | 99.9% | 1013.14 | 1 MG
SIYNFEKL TFA is a variant of the major MHC class I-restricted epitope SIINFEKL. It is an antigenic peptide that can stimulate specific T cells in experimental settings to study competitive interactions between T cells. SIYNFEKL TFA exhibits low affinity for the OT-I T cell receptor (TCR) and can be used for the detection of CD8+ T cells.
- Can stimulate specific T cells
- Used to study competitive interactions between T cells
- Exhibits low affinity for the OT-I T cell receptor (TCR)
- Can be used for the detection of CD8+ T cells
Medchemexpress LLC Veldoreotide TFA | 2126831-23-8 | 99.0% | 1237.33 | 5 MG
Veldoreotide TFA (DG3173) is a somatostatin analogue that binds to and activates somatostatin receptors (SSTR) 2, 4, and 5. It inhibits growth hormone (GH) secretion in adenomas and has potential use as a pain modulating agent.
- Activates somatostatin receptors 2, 4, and 5
- Inhibits growth hormone (GH) secretion in adenomas
- May be used as a pain-modulating agent
- Stimulates SST2, SST4, and SST5 receptors in HEK293 cells co-expressing these receptors with GIRK2 channels
- Inhibits SST4-expressing BON-1 cells at 10 μM for 24 hours
![Medchemexpress LLC [D-Lys6]-LH-RH TFA | 1253.41 (free base) | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC [D-Lys6]-LH-RH TFA | 1253.41 (free base) | 25 MG
[D-Lys6]-LH-RH TFA is a Luteinizing-hormone-releasing hormone (LHRH) analogue. It acts as a GnRH receptor agonist.
- Luteinizing-hormone-releasing hormone (LHRH) analogue
- GnRH receptor agonist
Supply Solutions Trifluoroacetic acid | 76-05-1 | 114.02 g/mol | 10x1ml
Trifluoroacetic acid | 76-05-1 | 114.02 g/mol | 10x1ml
Medchemexpress LLC Pep42 TFA | 99.6% | 1335.59 | 1 MG
Pep42 TFA is a cyclic peptide ligand of GPR78. It internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process. This product is for research use only and not sold to patients.
- Cyclic peptide ligand of GPR78
- Selectively internalizes into highly metastatic human melanoma cells
Medchemexpress LLC Stressin I TFA | 98.6% | 4472.20 | 5 MG
Stressin I TFA (Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)) TFA is a potent CRF1 receptor selective agonist with a Ki of 1.7 nM. It induces an increase in adrenocorticotropic hormone (ACTH) levels in rats. This product is for research use only and not sold to patients.
- Potent CRF1 receptor selective agonist
- Induces increase in adrenocorticotropic hormone (ACTH) levels
- White to off-white solid appearance
- For research use only
Medchemexpress LLC Pepinh-MYD TFA | 1421052-89-2 | 98.9% | 3388.03 | 5 MG
Pepinh-MYD TFA is a MyD88 inhibitor designed to interfere with MyD88-mediated TLR signaling pathways. It contains a domain sequence from MyD88 TIR and a protein transduction sequence, enabling cell membrane penetration and inhibition of related immune responses. This compound shows potential for studying the role of MyD88 in viral infections, including COVID-19.
- Acts as a MyD88 inhibitor
- Contains a domain sequence from MyD88 TIR
- Includes a protein transduction sequence for cell membrane penetration
- Interferes with MyD88-mediated TLR signaling pathways
- Inhibits immune responses
- Suitable for studying the role of MyD88 in viral infections
- Applicable in COVID-19 anti-virus research
Medchemexpress LLC NTPA TFA | 99.8% | 1773.36 (free base) | 500 UG
NTPA TFA is a polycarboxylic acid ligand that participates in the coordination reaction with metal ions to form complexes.
- Appearance: Solid
- Color: White to off-white
- Molecular formula: C82H161N31O12.xC2HF3O2
- Sequence: C17H35CONH-Pro-Lys-Lys-Lys-Arg-Lys-Val-Arg-Arg-Arg-Arg-NH2
- Storage: Sealed storage away from moisture; Powder: -80°C for 2 years, -20°C for 1 year; In solvent: -80°C for 6 months, -20°C for 1 month.
- Solubility: 50 mg/mL in DMSO (ultrasonic may be needed).
Medchemexpress LLC KRpep-2d TFA | 2098181-84-9 | 95.1% | 2675.03 | 2 MG
KRpep-2d is a potent inhibitor of K-Ras, designed to impede the proliferation of K-Ras-driven cancer cells. It is suitable for use in cancer research. The product possesses a cyclic structure, which is crucial for its K-Ras inhibitory activity, with specific amino acid residues (Leu77, Ile9, and Asp12) being critical for this function.
- Potently inhibits K-Ras activity.
- Reduces the proliferation of cancer cells driven by K-Ras.
- Features a cyclic structure important for its inhibitory action.
- Critical amino acid residues contribute to its effectiveness.
- Can be used for cancer research applications.
Medchemexpress LLC FRETS-VWF73 | 97.3% | 8314.28 | 100 UG
FRETS-VWF73 is a 73-amino-acid peptide that serves as a fluorogenic substrate for ADAMTS13 assay, with excitation at 340 nm and emission at 450 nm. It is utilized as a predictive tool for thrombotic thrombocytopenic purpura. This product is a light yellow to yellow solid with a molecular weight of 8314.28 and a purity of 97.3%.
- Serves as a fluorogenic substrate for ADAMTS13 assay
- Utilized as a predictive tool for thrombotic thrombocytopenic purpura
- Purity confirmed by HPLC
- Light yellow to yellow solid appearance
Medchemexpress LLC Stressin I TFA | 98.63% | 4472.20 (free base) | 1 MG
Stressin I TFA (Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)) is a potent and selective agonist for the CRF1 receptor, intended for research use only. It has been shown to increase adrenocorticotropic hormone (ACTH) levels in rats.
- Potent CRF1 receptor selective agonist
- Ki of 1.7 nM
- Increases adrenocorticotropic hormone (ACTH) levels in rats
Medchemexpress LLC Pep42 TFA | 99.6% | 1335.59 | 25 MG
Pep42 TFA is a cyclic peptide ligand of GPR78. It internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process. This product is for research use only.
- Cyclic peptide ligand of GPR78
- Internalizes selectively into highly metastatic human melanoma cells
- Receptor-mediated process
- Sequence: Cys-Thr-Val-Ala-Leu-Pro-Gly-Gly-Tyr-Val-Arg-Val-Cys (disulfide:Cys1-Cys13)
- Target: Others
- Pathway: Others
- Storage for powder: -80°C for 2 years, -20°C for 1 year
- Storage in solvent: -80°C for 6 months, -20°C for 1 month (sealed storage, away from moisture)
- Appearance: Solid
- Stable under recommended storage conditions
- Identified uses: Laboratory chemicals, manufacture of substances
Medchemexpress LLC Glycyl-Exatecan (TFA) | 1883333-57-0 | 96.9% | 25 MG
Glycyl-Exatecan TFA (Glycyl-DX-8951 TFA) is an anticancer agent and a derivative of Exatecan. It exhibits significant antitumor activity and is suitable for research on various cancers, including solid tumors.
- Derivative of Exatecan
- Anticancer agent
- Exhibits significant antitumor activity
- Suitable for research on various cancers
- Can be used for solid tumors research
Medchemexpress LLC 6bK TFA | 1774353-12-6 | 99.68% | 871.94 | 1 ML
6bK TFA is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. It has been shown to increase circulating insulin in high-fat-fed mice. Acute administration of 6bK TFA enhances glucose tolerance to oral glucose, particularly in high-fat-fed mice. This compound is suitable for use in type 2 diabetes research. It is intended for research use only and is not sold to patients.
- Potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM.
- Increases circulating insulin in high-fat-fed mice.
- Enhances glucose tolerance to oral glucose.
- Suitable for use in type 2 diabetes research.
- Intended for research use only.
Medchemexpress LLC F9170 (TFA) | 99.7% | 1983.3 g/mol | 5 MG
F9170 (TFA) is a laboratory chemical with 99.7% purity and a molecular weight of 1983.3 g/mol. It appears as a solid and is stable under recommended storage conditions. This product is intended for research use only and should be handled by suitably qualified and experienced scientists in appropriate facilities.
- Solid appearance
- Stable under recommended storage conditions
- Store powder at -80°C for up to 2 years or -20°C for up to 1 year
- Store in solvent at -80°C for up to 6 months or -20°C for up to 1 month (sealed storage, away from moisture)
- Suitable for shipping at room temperature if less than 2 weeks
- Requires handling in areas with appropriate exhaust ventilation
- Keep container tightly sealed in a cool, well-ventilated area
- Keep away from direct sunlight and sources of ignition